Interestingness

[jorenham]

Needed for semantic zooming.

The interestingness calculation needs to incorporate:

• large variants (>5kb, or configurable length)
• SNP from the list of 'known resistance mutations'
• NSY SNP/indel that phylogenetically converges in some meta-data field, for example DR. At the time of writing you don't have this information.
• NSY SNP/indel that has multiple independent evolutions in the phylogeny
• NSY SNP/indel not accounted in any other rule
• Rare SNP/indel (only occurs in <5% of strains). I don't know whether this is interesting or absolutely not, could go at bottom or top of the list. Number needs to be config option.
• Common SNP/indel (occurs in >75% of strains). I don't know whether this is interesting or absolutely not, could go at bottom or top of the list. Number needs to be config option.
• NSY SNP/indel that is phylogenetically inherited, i.e. only present in strains that come from the same ancestor
• SYN SNP (synonymous SNP)
  non-variabele node
• nodes with (majority) N's